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Vicodin® is the brand name buy hydrocodone for the combination of acetaminophen (Tylenol) and hydrocodone. Vicodin® is prescribed for moderate to moderately severe pain. Hydrocodone binds to the pain receptors in the brain so that the sensation of pain is reduced. Acetaminophen halts the production of prostaglandins which otherwise cause pain. Vicodin® is available in tablet, capsule, and liquid form and is taken every 4-6 hours by mouth. Since hydrocodone can be habit forming, care must be taken to follow the buy hydrocodone doctor's instructions when taking Vicodin®. Do not take a larger dose, or take it more frequently, or take it for longer than the doctor has prescribed.

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What is Hydrocodone?

A) Hydrocodone is an effective antitussive (anti-cough) agent, and as an opiate it is also an effective analgesic for mild buy hydrocodone to moderate pain control. Five mg of Hydrocodone is equivalent to 30 mg of codeine when administered orally. Early comparisons concluded that Hydrocodone and morphine were equivalent for pain control in humans. However, it is now considered that a dose of 15 mg (1/4 gr) of Hydrocodone is equivalent to 10 mg (1/6 gr) of morphine. Hydrocodone is considered to be morphine-like in all respects. There are over 200 products containing Hydrocodone in the U.S. In its most usual product forms Hydrocodone is combined with acetaminophen (Vicodin, Lortab), but it is also combined with aspirin (Lortab ASA), ibuprofen (Vicoprofen), and antihistamines (Hycomine). Both buy hydrocodone tablet and liquid forms of Hydrocodone are available (e.g., Tussionex) Hydrocodone will react as a normal opiate in the available field test kits. Hydrocodone is abused for its opiate-like effects. It is equivalent to morphine in relieving abstinence symptoms from chronic morphine administration. The Schedule III status of Hydrocodone-containing products has made them available to widespread diversion by "bogus call-in prescriptions" and thefts. Three dosage forms are typically buy hydrocodone found (5, 7.5, and 10 mg) and their behavioral effects can last up to 5 hours. The drug is most often administered orally. The growing awareness and concern about AIDS and blood-borne pathogens easily transmitted by syringe needle use, has made the oral bioavailability of Hydrocodone attractive to the typical opiate abuser.

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STUDY OBJECTIVES: To evaluate the efficacy and prevalence of side effects of hydrocodone versus codeine in acute pain syndromes. TYPE OF PARTICIPANTS/SETTING: Sixty-two consecutive adult emergency department buy hydrocodone patients 18 to 70 years old with acute musculoskeletal pain. Patients using other analgesics or having any contraindication to opioid therapy were excluded. In addition, 12 patients were excluded because of insufficient data or study dropout. DESIGN/INTERVENTIONS: In a randomized, double-blind prospective manner, patients received either 5 mg hydrocodone with 500 mg acetaminophen or 30 mg codeine buy hydrocodone with 500 mg acetaminophen to take on discharge from the ED and every four hours thereafter as needed for pain. MEASUREMENTS: Pain intensity was evaluated by a visual analog scale at zero, one, two, four, eight, 24, and 48 hours. Specific side effects were sought, along with the number of patients reporting inadequate analgesia. MAIN RESULTS: Data were obtained on 50 subjects (25 per group). Mean and median pain scores did not differ significantly at time zero (x vs y, 6.03 vs 5.99 and 6.8 vs 6.1, respectively) or subsequent intervals. Side effects were noted in eight hydrocodone/acetaminophen and 18 codeine/acetaminophen patients (P = .005). No significant differences in gastrointestinal side effects were reported; however, less nausea or vomiting was reported in the hydrocodone group (P = .23). Central nervous system side effects (sedation or lightheadedness) were reported in six hydrocodone/acetaminophen patients compared with 16 codeine/acetaminophen patients (P less than .005). In addition, no hydrocodone/acetaminophen patients reported inadequate analgesia compared with six codeine/acetaminophen patients buy hydrocodone (P less than .05). CONCLUSION: Although pain scores were not significantly different, hydrocodone may be a more effective analgesic than codeine in acute musculoskeletal pain, as demonstrated by significantly fewer treatment failures. Central nervous system side effects are less common with hydrocodone than with codeine.

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